Dr. Nicola Arrighi

Professional experience
Dates From May 2015 to today
Occupation or position held Coordinator of the Sperm Cryopreservation Center and PMA Andrologist Consultant
Name and address of the PMA employer
Clinical Institute of the City of Brescia

Dates From May 2016 to today
Occupation or position held Doctor in urological and andrological ultrasound service
Name and address of employer Affidea – Villa Salute in Manerbio (BS)

Dates From August 2012 to today
Occupation or position held Medical Specialist in Urology
Name and address of the employer UO of Urology
Clinical Institute of the City of Brescia

Dates From July 2007 to July 2012
Occupation or position held Doctor specializing in Urology
Name and address of employer Chair of Urology – U.O. of Urology
Civil Hospitals of Brescia

Dates From October 2009 to April 2010
Occupation or position held Doctor specializing in Urology
Name and address of employer Based at
Klinik und Poliklinik fuer Urologie – Dir. Prof P. Fornara
Martin Luther Universitaet Halle-Wittemberg
Halle an der Saale (D)
Education and training
Dates Year 2018
Title of qualification issued FECSM (Fellow of European Committee of Sexual Medicine)
Name and type of organization providing education and training Union Européenne des Médecins Specialistes (UEMS)

Dates Year 2015
Title of qualification awarded 2nd level Master in Reproductive Physiopathology
Name and type of organization providing education and training University of Padua

Dates Year 2014
Title of qualification awarded Postgraduate course in Reproductive Medicine
Name and type of organization providing education and training University of Padua

Dates July 2012
Title of qualification awarded Specialty in Urology
Thesis “Modulation of muscle cell proliferation by human detrusor mediated by muscarinic receptors.”
Name and type of organization providing education and training University of Brescia
Grade 50 cum laude / 50

Dates January 2011
Title of qualification awarded Diploma in Laparoscopic Surgery
Name and type of organization providing education and training Universitè Louis Pasteur
European Institute of Telesurgery – Strasbourg (F)

Dates November 2009
Title of qualification awarded Certificate in Good Clinical Practice
Name and type of organization providing education and training Brookwood International Academy (UK)

Dates March 2007 (1st session)
Title of qualification issued Registration in the Register of Doctors
Name and type of organization providing education and training Medical Association of the Province of Brescia

Dates October 2006 (1st session)
Title of qualification awarded Degree in Medicine and Surgery
Thesis “The muscarinic receptors in the human detrusor muscle.
Changes in expression induced by aging “
Rel. Prof. Sergio Cosciani Cunico
Name and type of organization providing education and training University of Brescia
Score 110 with honors / 110

Dates July 2000
Title of qualification awarded Level B1-DELF certification
Name and type of organization providing education and training Alliance Française

Dates July 2000
Title of qualification awarded Scientific high school diploma with linguistic address “Progetto Brocca”
Name and type of organization providing education and training Liceo E. Fermi
Salò
Score 100/100

Scientific Experiences

Author of over 30 indexed publications

in particular: Del Barba A, ARRIGHI N, et al (2020)
Positive nutraceuticals on sperm DNA damage in selected infertile patients with idiopathic high sperm DNA fragmentation
MINERVA ENDOCRINOL, 2020, 45: 89-96

ARRIGHI N et al (2013)
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt / PI3K and map kinases.
PHARMACOLOGICAL RESEARCH, 2013 Aug; 74: 1-6

ANTONELLI A, ARRIGHI N.et al (2012).
Surgical treatment of atypical metastasis from renal cell carcinoma (RCC).
BJU Int. 2012 Dec; 110 (11 Pt B): E559-63
(For this communication I was awarded the 2013 Bracci Prize)

ANTONELLI A, CALZA S, ARRIGHI N.et al (2012).
Clinical features and prognosis of patients with renal cancer and a second malignancy. UROLOGIC ONCOLOGY, vol. 30 (3): 294-300 ISSN: 1078-1439

ARRIGHI N. et al (2011).
Muscarinic receptors stimulate cell proliferation in the human urothelium-derived cell line UROtsa.
PHARMACOLOGICAL RESEARCH, vol. 64; p. 420-425,
ISSN: 1043-6618, doi: 10.1016 / j.phrs.2011.06.009

ANTONELLI A, ARRIGHI N et al (2010)
Prognostic value of cytogenetic analysis in clear cell renal carcinoma: a study on 131 patients with long-term follow-up.
ANTICANCER RESEARCH, vol. 30 (11); p. 4705-4709, ISSN: 0250-7005
ARRIGHI N et al (2009).
Molecular and Pharmacological Detection of Dopaminergic Receptors in the Human Male Urinary Tract.
NEUROUROLOGY AND URODYNAMICS, vol. 28 (4); p. 343-348, ISSN: 0733-2467

ARRIGHI N et al (2008).
Detection of Muscarinic Receptor Subtypes in Human Urinary Bladder Mucosa: Age and Gender-Dependent Modifications.
NEUROUROLOGY AND URODYNAMICS, vol. 27; p. 421-428, ISSN: 0733-2467

Author of at least 40 Communications at National and International Congresses
(of which about 20 as first author)

in particular: ARRIGHI N et al.
Poster at the “XXXIII Congress of European Society for Human Reproduction and Embriology”, Geneva 2017
Perspectival study about Testicular sperm aspiration as easy, outpatient procedure in support to Assisted Reproduction Technique in Obstructive Azoospermia: confrontation with Testicular Sperm Extraction

Communication by invitation to the INTERNATIONAL CONFERENCE FOR
ANTICANCER RESEARCH- 6-10 OCTOBER 2014 – Sithonia Greece
Role of acetylcholine as growth factor: focus on urinary bladder

Reading on invitation to VIII European Kidney Cancer Symposium (May 2013)
Surgical Management of Atypical metastasis from RCC

ARRIGHI N.
“Acetylcholine is a growth factor for detrusor leiomyocytes: molecular and pharmacological characterization” (2011)
Golden Comunication LXXXIV Congress of the Italian Society of Urology
Winner of the Diamond Award for Northern Italy

ARRIGHI N. et al
“Cholinergic stimulation of human detrusor muscle cells induces cell proliferation through different muscarinic receptor subtypes” (2010)
Golden Comunication LXXXIV Congress of the Italian Society of Urology
Best Communication of the SIUD-Verona Congress

ARRIGHI N. et al
“Muscarinic receptors stimulate the proliferation of leiomyocytes derived from human detrusor muscle” (2008)
Golden Comunication LXXXIV Congress of the Italian Society of Urology
Astellas Award SUN-SIU Congress “of the Centenary”

Participation in pharmacological studies

Researcher “Studio Orion” for the use of Solifenacin in the treatment of LUTS
– funded by Astellas (2013)

Researcher “Studio Record” (Italian Registry for Renal Conservative Surgery)
– funded by SIU and Nycomed (2009-2012)

Researcher “Study CS31” for the use of Degarelix in the treatment of Prostate Cancer
– funded by Ferring (2009-2010)

Reviewer Currently Reviewer of numerous international journals, including The Journal of Urology (official organ of the AUA, American Urologists Association), Clinical of Genitourinary Cancer (who named him “Outstanding Reviewer”), European Journal for Surgical Oncology

Courses & Congresses

I participated in about 80 Courses and Congresses, with particular interest in Andrology, Laparoscopic Surgery, the treatment of Renal, Bladder and Alta Via Escretrice Neoplasms.